At the same time, big pharma is in hot pursuit of the next blockbuster drug. Many of the industry’s most successful franchises, from Gilead’s Hepatitis C cure and Biogen Inc’s multiple sclerosis treatments, to AbbVie Inc’s arthritis drug Humira, are all bracing for declining revenues as patents age and competition heats up. Valuations of biotechnology companies that could be acquisition targets for major drug firms are still hovering near historic lows after being dragged down by election-season political criticism of high drug prices. “Tax repatriation is a more likely situation now, benefiting large biotechs and (pharmaceutical companies) with significant offshore cash and a desire to buy mid-cap companies,” RBC Capital equity analyst Michael Yee wrote in a research note. The last time tax considerations fueled a wave of dealmaking in the pharmaceutical industry was in 2014, when companies sought to redomicile abroad through acquisitions, referred to as corporate inversions. But U.S. President Barack Obama subsequently announced curbs to limit inversions, culminating in Pfizer abandoning its $160-billion agreement to acquire Allergan Plc, the biggest attempted merger of all time. Pharmaceutical M&A involving U.S. companies has been around $90 billion year-to-date, down from nearly $270 billion the year before. On the hunt Executives at Pfizer, which has already said it is looking to do more deals after its $14-billion acquisition of cancer drugmaker Medivation Inc, have told investors in private meetings that its M&A appetite would grow even bigger if it could bring home its more than $70 billion in overseas cash, according to people familiar with the matter. Pfizer could potentially use its newfound firepower to buy a company as large as Bristol-Myers Squibb Co, a $92-billion market capitalization cancer drugmaker that fueled takeover speculation after a disappointing drug trial in August sent its stock down more than 25 percent.
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Getting a correct diagnosis is the first step to managing migraine, and I have always found it useful to keep a headache diary or calendar to record the severity of my migraine headache pain, and my response to migraine drugs treatment. However, it is largely recognized the current while some pain relief is available through the use of drugs, this is not going to be cure for the problem. Making matters more complex, if the diagnosis is not positional vertigo, the treatment won’t work. The physiotherapist is actually directly associated with the social and health care industry. Without doubt, a physiotherapist has to do a lot of hard work with strong determination but starting a career as a physiotherapist can be rich with knowledge and highly rewarding. Support, love and understanding are of primary importance for those suffering with this affliction. Not only that, but he or she is contributing to society to a great extent. This disorder is not something that will show up on an MRI examination.